Endocrine Abstracts

The pituitary gland is altered by both anatomical and physiological changes during pregnancy. The most striking finding is the physiological enlargement of the pituitary gland as a result of lactotroph hyperplasia. Hormonal evaluation of pregnant women requires special consideration due to the emergence of the placenta as a new source of hormone production, changes in binding globulin levels and resistance to hormones such as glucocorticoids.Pituitary ad...

Objective: Hyperprolactinemia is reported to be associated with impaired glucose metabolism, and low-grade inflammation. There is some data regarding increased oxidative stress- particularly protein oxidation in the conditions like metabolic syndrome or diabetes, but not in hyperprolactinemic subjects in the literature. We aimed to investigate advanced oxidation protein product (AOPP) levels-an established marker of protein oxidation and antioxidant thiol levels in hyperprolac...

Background: Cushing’s syndrome is a well-known risk factor for endothelial dysfunction, cardiovascular morbidity and mortality.Objectives: We aimed to prospectively investigate changes in metabolic and cardiovascular parameters and their correlations with markers of endothelial function in patients with endogenous Cushing syndrome following remission. Methods: Adult patients newly diagnosed with endogenous Cushing’s Syndr...